General Information

  • ID:  hor002757
  • Uniprot ID:  A0A8J5JKT7
  • Protein name:  NA
  • Gene name:  Tth1-L1
  • Organism:  Homarus americanus (American lobster)
  • Family:  Thymosin beta family
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Homarus (genus), Nephropidae (family), Nephropoidea (superfamily), Astacidea (infraorder), Pleocyemata (suborder), Decapoda (order), Eucarida (superorder), Eumalacostraca (subclass), Malacostraca (class), Multicrustacea (superclass), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  GO:0003785 actin monomer binding
  • GO BP:  GO:0007015 actin filament organization
  • GO CC:  NA

Sequence Information

  • Sequence:  DLPKVDTALK
  • Length:  10(9-18)
  • Propeptide:  MSTETHLKDLPKVDTALKGQLEAFTPDKLKKIDTEEKVTLPTKDDVEQEKQHLELVDNIKQFRSDKLKRTSTSEKIVLPTPEGMVSTEARLSIIKLVSTRHALHPMILLLHTG
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor002757_AF2.pdbhor002757_ESM.pdb

Physical Information

Mass: 126002 Formula: C49H86N12O16
Absent amino acids: CEFGHIMNQRSWY Common amino acids: DKL
pI: 6.45 Basic residues: 2
Polar residues: 1 Hydrophobic residues: 4
Hydrophobicity: -35 Boman Index: -1542
Half-Life: 1.1 hour Half-Life Yeast: 3 min
Half-Life E.Coli: >10 hour Aliphatic Index 117
Instability Index: -1878 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  18304551
  • Title:  Mass Spectral Characterization of Peptide Transmitters/Hormones in the Nervous System and Neuroendocrine Organs of the American Lobster Homarus Americanus